BDBM50234917 CHEMBL4080163

SMILES: Cc1cccc2c1nc(CCC(O)=O)[nH]c2=O

InChI Key: InChIKey=OOIMOZIUYZYXLA-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50234917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50234917 (CHEMBL4080163) Show SMILES Cc1cccc2c1nc(CCC(O)=O)[nH]c2=O Show InChI InChI=1S/C12H12N2O3/c1-7-3-2-4-8-11(7)13-9(14-12(8)17)5-6-10(15)16/h2-4H,5-6H2,1H3,(H,15,16)(H,13,14,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-GST-tagged TNKS2 (849 to 1166 residues) expressed in baculovirus infected Sf9 cells using biotinylated...				J Med Chem 60: 814-820 (2017) BindingDB Entry DOI: 10.7270/Q20R9RPP
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM50234917 (CHEMBL4080163) Show SMILES Cc1cccc2c1nc(CCC(O)=O)[nH]c2=O Show InChI InChI=1S/C12H12N2O3/c1-7-3-2-4-8-11(7)13-9(14-12(8)17)5-6-10(15)16/h2-4H,5-6H2,1H3,(H,15,16)(H,13,14,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged TNKS1 (1001 to 1327 residues) expressed in baculovirus infected sf9 cells using TACS-Sapphire a...				J Med Chem 60: 814-820 (2017) BindingDB Entry DOI: 10.7270/Q20R9RPP
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50234917 (CHEMBL4080163) Show SMILES Cc1cccc2c1nc(CCC(O)=O)[nH]c2=O Show InChI InChI=1S/C12H12N2O3/c1-7-3-2-4-8-11(7)13-9(14-12(8)17)5-6-10(15)16/h2-4H,5-6H2,1H3,(H,15,16)(H,13,14,17)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PARP1 expressed in Baculovirus infected Sf9 cells using TACS-Sapphire as substrate ...				J Med Chem 60: 814-820 (2017) BindingDB Entry DOI: 10.7270/Q20R9RPP
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50234917 (CHEMBL4080163) Show SMILES Cc1cccc2c1nc(CCC(O)=O)[nH]c2=O Show InChI InChI=1S/C12H12N2O3/c1-7-3-2-4-8-11(7)13-9(14-12(8)17)5-6-10(15)16/h2-4H,5-6H2,1H3,(H,15,16)(H,13,14,17)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal GST-tagged PARP1 expressed in Baculovirus infected Sf9 cells using TACS-Sapphire as substrate ...				J Med Chem 60: 814-820 (2017) BindingDB Entry DOI: 10.7270/Q20R9RPP
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Homo sapiens (Human))	BDBM50234917 (CHEMBL4080163) Show SMILES Cc1cccc2c1nc(CCC(O)=O)[nH]c2=O Show InChI InChI=1S/C12H12N2O3/c1-7-3-2-4-8-11(7)13-9(14-12(8)17)5-6-10(15)16/h2-4H,5-6H2,1H3,(H,15,16)(H,13,14,17)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells measured after 1 hr by ch...				J Med Chem 60: 814-820 (2017) BindingDB Entry DOI: 10.7270/Q20R9RPP
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 2 (Homo sapiens (Human))	BDBM50234917 (CHEMBL4080163) Show SMILES Cc1cccc2c1nc(CCC(O)=O)[nH]c2=O Show InChI InChI=1S/C12H12N2O3/c1-7-3-2-4-8-11(7)13-9(14-12(8)17)5-6-10(15)16/h2-4H,5-6H2,1H3,(H,15,16)(H,13,14,17)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PARP2 (2 to 583 residues) expressed in baculovirus infected Sf9 cells measured after 1 hr by ch...				J Med Chem 60: 814-820 (2017) BindingDB Entry DOI: 10.7270/Q20R9RPP
					More data for this Ligand-Target Pair