BDBM50235312 6-(3-chloro-2-fluorobenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid::CHEMBL270717

SMILES: OC(=O)c1cnc2ccc(Cc3cccc(Cl)c3F)cc2c1O

InChI Key: InChIKey=NNCDBLPXXVWRGR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50235312   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50235312 (6-(3-chloro-2-fluorobenzyl)-4-oxo-1,4-dihydroquino...) Show SMILES OC(=O)c1cnc2ccc(Cc3cccc(Cl)c3F)cc2c1O Show InChI InChI=1S/C17H11ClFNO3/c18-13-3-1-2-10(15(13)19)6-9-4-5-14-11(7-9)16(21)12(8-20-14)17(22)23/h1-5,7-8H,6H2,(H,20,21)(H,22,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Central Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 integrase strand transfer activity				J Med Chem 49: 1506-8 (2006) Article DOI: 10.1021/jm0600139 BindingDB Entry DOI: 10.7270/Q2H131NP
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50235312 (6-(3-chloro-2-fluorobenzyl)-4-oxo-1,4-dihydroquino...) Show SMILES OC(=O)c1cnc2ccc(Cc3cccc(Cl)c3F)cc2c1O Show InChI InChI=1S/C17H11ClFNO3/c18-13-3-1-2-10(15(13)19)6-9-4-5-14-11(7-9)16(21)12(8-20-14)17(22)23/h1-5,7-8H,6H2,(H,20,21)(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	4.36E+7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Human immunodeficiency virus 1 integrase strand transfer activity				Citation and Details Article DOI: 10.1007/s00044-011-9593-5 BindingDB Entry DOI: 10.7270/Q26976G0
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50235312 (6-(3-chloro-2-fluorobenzyl)-4-oxo-1,4-dihydroquino...) Show SMILES OC(=O)c1cnc2ccc(Cc3cccc(Cl)c3F)cc2c1O Show InChI InChI=1S/C17H11ClFNO3/c18-13-3-1-2-10(15(13)19)6-9-4-5-14-11(7-9)16(21)12(8-20-14)17(22)23/h1-5,7-8H,6H2,(H,20,21)(H,22,23)	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of HIV1 integrase strand transfer activity				J Med Chem 51: 1136-44 (2008) Article DOI: 10.1021/jm070609b BindingDB Entry DOI: 10.7270/Q25Q4ZVQ
					More data for this Ligand-Target Pair