null

SMILES: CN(C)CCOc1cn2ncnc(Oc3ccc(NC(=O)CC(=O)Nc4ccc(F)cc4)cc3F)c2c1C

InChI Key: InChIKey=HWOXQSUVADVKLF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235563 (CHEMBL254907 | N1-(4-(6-(2-(dimethylamino)ethoxy)-...) Show SMILES CN(C)CCOc1cn2ncnc(Oc3ccc(NC(=O)CC(=O)Nc4ccc(F)cc4)cc3F)c2c1C Show InChI InChI=1S/C26H26F2N6O4/c1-16-22(37-11-10-33(2)3)14-34-25(16)26(29-15-30-34)38-21-9-8-19(12-20(21)28)32-24(36)13-23(35)31-18-6-4-17(27)5-7-18/h4-9,12,14-15H,10-11,13H2,1-3H3,(H,31,35)(H,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human c-MET				Eur J Med Chem 46: 3675-80 (2011) Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235563 (CHEMBL254907 | N1-(4-(6-(2-(dimethylamino)ethoxy)-...) Show SMILES CN(C)CCOc1cn2ncnc(Oc3ccc(NC(=O)CC(=O)Nc4ccc(F)cc4)cc3F)c2c1C Show InChI InChI=1S/C26H26F2N6O4/c1-16-22(37-11-10-33(2)3)14-34-25(16)26(29-15-30-34)38-21-9-8-19(12-20(21)28)32-24(36)13-23(35)31-18-6-4-17(27)5-7-18/h4-9,12,14-15H,10-11,13H2,1-3H3,(H,31,35)(H,32,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression system				Bioorg Med Chem Lett 18: 1945-51 (2008) Article DOI: 10.1016/j.bmcl.2008.01.121 BindingDB Entry DOI: 10.7270/Q2125SFV
					More data for this Ligand-Target Pair