null

SMILES: NCC1CCN(Cc2ccn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c23)CC1

InChI Key: InChIKey=VRXCVXPQSXIQRY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235566 (1-(4-(5-((4-(aminomethyl)piperidin-1-yl)methyl)pyr...) Show SMILES NCC1CCN(Cc2ccn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c23)CC1 Show InChI InChI=1S/C28H29F2N7O3/c29-21-3-1-18(2-4-21)13-25(38)35-28(39)34-22-5-6-24(23(30)14-22)40-27-26-20(9-12-37(26)33-17-32-27)16-36-10-7-19(15-31)8-11-36/h1-6,9,12,14,17,19H,7-8,10-11,13,15-16,31H2,(H2,34,35,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human c-MET				Eur J Med Chem 46: 3675-80 (2011) Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235566 (1-(4-(5-((4-(aminomethyl)piperidin-1-yl)methyl)pyr...) Show SMILES NCC1CCN(Cc2ccn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c23)CC1 Show InChI InChI=1S/C28H29F2N7O3/c29-21-3-1-18(2-4-21)13-25(38)35-28(39)34-22-5-6-24(23(30)14-22)40-27-26-20(9-12-37(26)33-17-32-27)16-36-10-7-19(15-31)8-11-36/h1-6,9,12,14,17,19H,7-8,10-11,13,15-16,31H2,(H2,34,35,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression system				Bioorg Med Chem Lett 18: 1945-51 (2008) Article DOI: 10.1016/j.bmcl.2008.01.121 BindingDB Entry DOI: 10.7270/Q2125SFV
					More data for this Ligand-Target Pair