null

SMILES: CN1CCN(CCOc2cn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c3c2C)CC1

InChI Key: InChIKey=JGKKVHUMEAYNGF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235567 (1-(3-fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CCOc2cn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c3c2C)CC1 Show InChI InChI=1S/C29H31F2N7O4/c1-19-25(41-14-13-37-11-9-36(2)10-12-37)17-38-27(19)28(32-18-33-38)42-24-8-7-22(16-23(24)31)34-29(40)35-26(39)15-20-3-5-21(30)6-4-20/h3-8,16-18H,9-15H2,1-2H3,(H2,34,35,39,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of human c-MET				Eur J Med Chem 46: 3675-80 (2011) Article DOI: 10.1016/j.ejmech.2011.05.031 BindingDB Entry DOI: 10.7270/Q2891676
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50235567 (1-(3-fluoro-4-(5-methyl-6-(2-(4-methylpiperazin-1-...) Show SMILES CN1CCN(CCOc2cn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c3c2C)CC1 Show InChI InChI=1S/C29H31F2N7O4/c1-19-25(41-14-13-37-11-9-36(2)10-12-37)17-38-27(19)28(32-18-33-38)42-24-8-7-22(16-23(24)31)34-29(40)35-26(39)15-20-3-5-21(30)6-4-20/h3-8,16-18H,9-15H2,1-2H3,(H2,34,35,39,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression system				Bioorg Med Chem Lett 18: 1945-51 (2008) Article DOI: 10.1016/j.bmcl.2008.01.121 BindingDB Entry DOI: 10.7270/Q2125SFV
					More data for this Ligand-Target Pair