BDBM50235760 CHEMBL429853::{4-[2-((S)-1-amino-2-methyl-propyl)-4-methyl-phenyl]-piperazin-1-yl}-[(2S,3R)-3-(4-chloro-phenyl)-1-cyclobutanecarbonyl-pyrrolidin-2-yl]-methanone

SMILES: CC(C)[C@H](N)c1cc(C)ccc1N1CCN(CC1)C(=O)[C@@H]1[C@H](CCN1C(=O)C1CCC1)c1ccc(Cl)cc1

InChI Key: InChIKey=PXPQDTMYWPFLRO-IGBKUBFESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50235760 (CHEMBL429853 | {4-[2-((S)-1-amino-2-methyl-propyl)...) Show SMILES CC(C)[C@H](N)c1cc(C)ccc1N1CCN(CC1)C(=O)[C@@H]1[C@H](CCN1C(=O)C1CCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C31H41ClN4O2/c1-20(2)28(33)26-19-21(3)7-12-27(26)34-15-17-35(18-16-34)31(38)29-25(22-8-10-24(32)11-9-22)13-14-36(29)30(37)23-5-4-6-23/h7-12,19-20,23,25,28-29H,4-6,13-18,33H2,1-3H3/t25-,28+,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125]NDPMSH from human MC4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 1931-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.125 BindingDB Entry DOI: 10.7270/Q2WD409C
					More data for this Ligand-Target Pair