BDBM50235781 1-((2R,3R)-2-(1-(2-((S)-1-amino-2-methylpropyl)-4-methylphenyl)piperazine-4-carbonyl)-3-(4-fluorophenyl)pyrrolidin-1-yl)ethanone::CHEMBL256540

SMILES: CC(C)[C@H](N)c1cc(C)ccc1N1CCN(CC1)C(=O)[C@H]1[C@H](CCN1C(C)=O)c1ccc(F)cc1

InChI Key: InChIKey=BNWZLYBYTDGSQA-DURWQBQJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50235781 (1-((2R,3R)-2-(1-(2-((S)-1-amino-2-methylpropyl)-4-...) Show SMILES CC(C)[C@H](N)c1cc(C)ccc1N1CCN(CC1)C(=O)[C@H]1[C@H](CCN1C(C)=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H37FN4O2/c1-18(2)26(30)24-17-19(3)5-10-25(24)31-13-15-32(16-14-31)28(35)27-23(11-12-33(27)20(4)34)21-6-8-22(29)9-7-21/h5-10,17-18,23,26-27H,11-16,30H2,1-4H3/t23-,26+,27-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125]NDPMSH from human MC4 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 1931-8 (2008) Article DOI: 10.1016/j.bmcl.2008.01.125 BindingDB Entry DOI: 10.7270/Q2WD409C
					More data for this Ligand-Target Pair