BDBM50235950 CHEMBL4087750

SMILES: COc1cc(NC(=O)c2ccc(c(CCN(C)C3CC3)c2)-c2ccccc2OC(F)(F)F)ccc1S(N)(=O)=O

InChI Key: InChIKey=YKIVLTRWSMHOQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235950   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
mineralocorticoid (RAT)	BDBM50235950 (CHEMBL4087750) Show SMILES COc1cc(NC(=O)c2ccc(c(CCN(C)C3CC3)c2)-c2ccccc2OC(F)(F)F)ccc1S(N)(=O)=O Show InChI InChI=1S/C27H28F3N3O5S/c1-33(20-9-10-20)14-13-17-15-18(7-11-21(17)22-5-3-4-6-23(22)38-27(28,29)30)26(34)32-19-8-12-25(39(31,35)36)24(16-19)37-2/h3-8,11-12,15-16,20H,9-10,13-14H2,1-2H3,(H,32,34)(H2,31,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
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