BDBM50235951 CHEMBL4066419

SMILES: COc1cc(NC(=O)c2ccc(c(CCN3CC(C)OC(C)C3)c2)-c2ccccc2OC(F)(F)F)ccc1S(N)(=O)=O

InChI Key: InChIKey=RQTMQHGUBWWJDZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
mineralocorticoid (RAT)	BDBM50235951 (CHEMBL4066419) Show SMILES COc1cc(NC(=O)c2ccc(c(CCN3CC(C)OC(C)C3)c2)-c2ccccc2OC(F)(F)F)ccc1S(N)(=O)=O Show InChI InChI=1S/C29H32F3N3O6S/c1-18-16-35(17-19(2)40-18)13-12-20-14-21(8-10-23(20)24-6-4-5-7-25(24)41-29(30,31)32)28(36)34-22-9-11-27(42(33,37)38)26(15-22)39-3/h4-11,14-15,18-19H,12-13,16-17H2,1-3H3,(H,34,36)(H2,33,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (IQM-CSIC) Curated by ChEMBL					Assay Description Displacement of [3H]-Aldosterone from MR in rat renal soluble fraction measured after 18 hrs in presence of glucocorticoid receptor antagonist RU-486...				J Med Chem 60: 2629-2650 (2017) Article DOI: 10.1021/acs.jmedchem.6b01065 BindingDB Entry DOI: 10.7270/Q2HD7XXB
					More data for this Ligand-Target Pair