BDBM50235987 CHEMBL4100336

SMILES: CC(Oc1ccc(Cc2ccc(OCc3nc(oc3C)-c3ccccc3)cc2)cc1)C(O)=O

InChI Key: InChIKey=YDYDOQPEPIKOKN-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50235987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50235987 (CHEMBL4100336) Show SMILES CC(Oc1ccc(Cc2ccc(OCc3nc(oc3C)-c3ccccc3)cc2)cc1)C(O)=O Show InChI InChI=1S/C27H25NO5/c1-18-25(28-26(33-18)22-6-4-3-5-7-22)17-31-23-12-8-20(9-13-23)16-21-10-14-24(15-11-21)32-19(2)27(29)30/h3-15,19H,16-17H2,1-2H3,(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of FTase-catalyzed incorporation of [3H]- FPP radioligand into recombinant Ha-Ras by 50% at an enzyme concentration of 1 nM.				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50235987 (CHEMBL4100336) Show SMILES CC(Oc1ccc(Cc2ccc(OCc3nc(oc3C)-c3ccccc3)cc2)cc1)C(O)=O Show InChI InChI=1S/C27H25NO5/c1-18-25(28-26(33-18)22-6-4-3-5-7-22)17-31-23-12-8-20(9-13-23)16-21-10-14-24(15-11-21)32-19(2)27(29)30/h3-15,19H,16-17H2,1-2H3,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari"Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of [3H]- FPP incorporation into recombinant Ha-Ras by farnesyl transferase at 10 pM				Eur J Med Chem 127: 379-397 (2017) Article DOI: 10.1016/j.ejmech.2016.12.047 BindingDB Entry DOI: 10.7270/Q2474D4J
					More data for this Ligand-Target Pair