null

SMILES: CCCCNc1nc(N)nc(C)c1CCCN1C(=O)c2ccccc2C1=O

InChI Key: InChIKey=VMDBQXAIUGAYHI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236166 (CHEMBL4069667) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C20H25N5O2/c1-3-4-11-22-17-14(13(2)23-20(21)24-17)10-7-12-25-18(26)15-8-5-6-9-16(15)19(25)27/h5-6,8-9H,3-4,7,10-12H2,1-2H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236166 (CHEMBL4069667) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C20H25N5O2/c1-3-4-11-22-17-14(13(2)23-20(21)24-17)10-7-12-25-18(26)15-8-5-6-9-16(15)19(25)27/h5-6,8-9H,3-4,7,10-12H2,1-2H3,(H3,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	453	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair