null

SMILES: CCCCNc1nc(N)nc(C)c1CCCN(C)CCOC

InChI Key: InChIKey=VDPBSLCNBPIBGQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236177 (CHEMBL4069818) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN(C)CCOC Show InChI InChI=1S/C16H31N5O/c1-5-6-9-18-15-14(13(2)19-16(17)20-15)8-7-10-21(3)11-12-22-4/h5-12H2,1-4H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	203	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236177 (CHEMBL4069818) Show SMILES CCCCNc1nc(N)nc(C)c1CCCN(C)CCOC Show InChI InChI=1S/C16H31N5O/c1-5-6-9-18-15-14(13(2)19-16(17)20-15)8-7-10-21(3)11-12-22-4/h5-12H2,1-4H3,(H3,17,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair