null

SMILES: CCCCNc1nc(N)nc(C)c1CCCC(C)(C)O

InChI Key: InChIKey=FFHKACIWNAOTCH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50236180   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 7 (Homo sapiens (Human))	BDBM50236180 (CHEMBL4084584) Show SMILES CCCCNc1nc(N)nc(C)c1CCCC(C)(C)O Show InChI InChI=1S/C15H28N4O/c1-5-6-10-17-13-12(8-7-9-15(3,4)20)11(2)18-14(16)19-13/h20H,5-10H2,1-4H3,(H3,16,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.89E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR7 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50236180 (CHEMBL4084584) Show SMILES CCCCNc1nc(N)nc(C)c1CCCC(C)(C)O Show InChI InChI=1S/C15H28N4O/c1-5-6-10-17-13-12(8-7-9-15(3,4)20)11(2)18-14(16)19-13/h20H,5-10H2,1-4H3,(H3,16,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Agonist activity at human TLR8 expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as induction of NF-kappaB/AP-1 promoter...				J Med Chem 60: 2084-2098 (2017) Article DOI: 10.1021/acs.jmedchem.6b01860 BindingDB Entry DOI: 10.7270/Q27083QG
					More data for this Ligand-Target Pair