BDBM50236710 CHEMBL4071804

SMILES: Fc1ccc(cc1)S(=O)(=O)c1cnc2c(F)c(Cl)ccc2c1-c1ccc(Cl)cc1

InChI Key: InChIKey=UJHOFFOLNQULBJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50236710 (CHEMBL4071804) Show SMILES Fc1ccc(cc1)S(=O)(=O)c1cnc2c(F)c(Cl)ccc2c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H11Cl2F2NO2S/c22-13-3-1-12(2-4-13)19-16-9-10-17(23)20(25)21(16)26-11-18(19)29(27,28)15-7-5-14(24)6-8-15/h1-11H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 mins				J Med Chem 60: 2470-2484 (2017) Article DOI: 10.1021/acs.jmedchem.6b01858 BindingDB Entry DOI: 10.7270/Q2RV0R05
					More data for this Ligand-Target Pair