BDBM50238368 CHEMBL4104348

SMILES: CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=O)c2cccc(Cl)c2)cc1

InChI Key: InChIKey=HQPOHZILTINXAI-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50238368 (CHEMBL4104348) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C28H30ClNO4/c1-4-32-23-8-10-24(11-9-23)33-18-27-26-13-12-25(34-19(2)3)17-20(26)14-15-30(27)28(31)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50238368 (CHEMBL4104348) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C28H30ClNO4/c1-4-32-23-8-10-24(11-9-23)33-18-27-26-13-12-25(34-19(2)3)17-20(26)14-15-30(27)28(31)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair