BDBM50238385 CHEMBL260546::N-(4-(5-cyanobenzo[d]oxazol-2-yl)phenyl)-2-(o-tolyloxy)acetamide

SMILES: Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(ccc2o1)C#N

InChI Key: InChIKey=IYCJSGBIJLZWDK-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50238385   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50238385 (CHEMBL260546 | N-(4-(5-cyanobenzo[d]oxazol-2-yl)ph...) Show SMILES Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(ccc2o1)C#N Show InChI InChI=1S/C23H17N3O3/c1-15-4-2-3-5-20(15)28-14-22(27)25-18-9-7-17(8-10-18)23-26-19-12-16(13-24)6-11-21(19)29-23/h2-12H,14H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CETP assessed as cholesteryl ester transfer activity				Bioorg Med Chem Lett 20: 1019-22 (2010) Article DOI: 10.1016/j.bmcl.2009.12.046 BindingDB Entry DOI: 10.7270/Q2MW2H8Q
					More data for this Ligand-Target Pair
Choline/ethanolaminephosphotransferase 1 (Homo sapiens)	BDBM50238385 (CHEMBL260546 | N-(4-(5-cyanobenzo[d]oxazol-2-yl)ph...) Show SMILES Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(ccc2o1)C#N Show InChI InChI=1S/C23H17N3O3/c1-15-4-2-3-5-20(15)28-14-22(27)25-18-9-7-17(8-10-18)23-26-19-12-16(13-24)6-11-21(19)29-23/h2-12H,14H2,1H3,(H,25,27)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description inhibition of human CEPT assessed as cholesteryl ester transfer by fluorescence transfer assay				Bioorg Med Chem Lett 20: 346-9 (2010) Article DOI: 10.1016/j.bmcl.2009.10.099 BindingDB Entry DOI: 10.7270/Q2FJ2KKK
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50238385 (CHEMBL260546 | N-(4-(5-cyanobenzo[d]oxazol-2-yl)ph...) Show SMILES Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(ccc2o1)C#N Show InChI InChI=1S/C23H17N3O3/c1-15-4-2-3-5-20(15)28-14-22(27)25-18-9-7-17(8-10-18)23-26-19-12-16(13-24)6-11-21(19)29-23/h2-12H,14H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50238385 (CHEMBL260546 | N-(4-(5-cyanobenzo[d]oxazol-2-yl)ph...) Show SMILES Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(ccc2o1)C#N Show InChI InChI=1S/C23H17N3O3/c1-15-4-2-3-5-20(15)28-14-22(27)25-18-9-7-17(8-10-18)23-26-19-12-16(13-24)6-11-21(19)29-23/h2-12H,14H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair