BDBM50238457 CHEMBL4069354

SMILES: OCC1CCN(CC1)C(=O)c1nnn(n1)-c1cccc2ccccc12

InChI Key: InChIKey=RODMMJICQSCKCM-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238457 (CHEMBL4069354) Show SMILES OCC1CCN(CC1)C(=O)c1nnn(n1)-c1cccc2ccccc12 Show InChI InChI=1S/C18H19N5O2/c24-12-13-8-10-22(11-9-13)18(25)17-19-21-23(20-17)16-7-3-5-14-4-1-2-6-15(14)16/h1-7,13,24H,8-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238457 (CHEMBL4069354) Show SMILES OCC1CCN(CC1)C(=O)c1nnn(n1)-c1cccc2ccccc12 Show InChI InChI=1S/C18H19N5O2/c24-12-13-8-10-22(11-9-13)18(25)17-19-21-23(20-17)16-7-3-5-14-4-1-2-6-15(14)16/h1-7,13,24H,8-12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair