BDBM50238467 CHEMBL4063613

SMILES: COCCNC(=O)c1sc(nc1C)-c1cccc2ccccc12

InChI Key: InChIKey=BAVZCUNVZZDWDR-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238467   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238467 (CHEMBL4063613) Show SMILES COCCNC(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C18H18N2O2S/c1-12-16(17(21)19-10-11-22-2)23-18(20-12)15-9-5-7-13-6-3-4-8-14(13)15/h3-9H,10-11H2,1-2H3,(H,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238467 (CHEMBL4063613) Show SMILES COCCNC(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C18H18N2O2S/c1-12-16(17(21)19-10-11-22-2)23-18(20-12)15-9-5-7-13-6-3-4-8-14(13)15/h3-9H,10-11H2,1-2H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238467 (CHEMBL4063613) Show SMILES COCCNC(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C18H18N2O2S/c1-12-16(17(21)19-10-11-22-2)23-18(20-12)15-9-5-7-13-6-3-4-8-14(13)15/h3-9H,10-11H2,1-2H3,(H,19,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair