BDBM50238470 CHEMBL4064423

SMILES: CN1CCN(CC1)C(=O)c1sc(nc1C)-c1cccc2ccccc12

InChI Key: InChIKey=VSAPOZMERHDMFC-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238470 (CHEMBL4064423) Show SMILES CN1CCN(CC1)C(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C20H21N3OS/c1-14-18(20(24)23-12-10-22(2)11-13-23)25-19(21-14)17-9-5-7-15-6-3-4-8-16(15)17/h3-9H,10-13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238470 (CHEMBL4064423) Show SMILES CN1CCN(CC1)C(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C20H21N3OS/c1-14-18(20(24)23-12-10-22(2)11-13-23)25-19(21-14)17-9-5-7-15-6-3-4-8-16(15)17/h3-9H,10-13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2B receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238470 (CHEMBL4064423) Show SMILES CN1CCN(CC1)C(=O)c1sc(nc1C)-c1cccc2ccccc12 Show InChI InChI=1S/C20H21N3OS/c1-14-18(20(24)23-12-10-22(2)11-13-23)25-19(21-14)17-9-5-7-15-6-3-4-8-16(15)17/h3-9H,10-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at recombinant human 5-HT2A receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...				J Med Chem 60: 6166-6190 (2017) Article DOI: 10.1021/acs.jmedchem.7b00385 BindingDB Entry DOI: 10.7270/Q25M680Z
					More data for this Ligand-Target Pair