BDBM50238559 CHEMBL4090927

SMILES: Cc1ccccc1CNC(=O)n1c(N)nc2ccccc12

InChI Key: InChIKey=UOLYBTCCKNBIKO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50238559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid ceramidase (Homo sapiens (Human))	BDBM50238559 (CHEMBL4090927) Show SMILES Cc1ccccc1CNC(=O)n1c(N)nc2ccccc12 Show InChI InChI=1S/C16H16N4O/c1-11-6-2-3-7-12(11)10-18-16(21)20-14-9-5-4-8-13(14)19-15(20)17/h2-9H,10H2,1H3,(H2,17,19)(H,18,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...				J Med Chem 60: 5800-5815 (2017) Article DOI: 10.1021/acs.jmedchem.7b00472 BindingDB Entry DOI: 10.7270/Q2SB481G
					More data for this Ligand-Target Pair