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SMILES: Nc1nc2ccccc2n1C(=O)NCc1ccccc1

InChI Key: InChIKey=DIVMYJFDOSCIEC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50238567   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acid ceramidase


(Homo sapiens (Human))		BDBM50238567
PNG
(CHEMBL4075647)
Show SMILES Nc1nc2ccccc2n1C(=O)NCc1ccccc1
Show InChI InChI=1S/C15H14N4O/c16-14-18-12-8-4-5-9-13(12)19(14)15(20)17-10-11-6-2-1-3-7-11/h1-9H,10H2,(H2,16,18)(H,17,20)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 29n/an/an/an/an/an/a



Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...

J Med Chem 60: 5800-5815 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00472
BindingDB Entry DOI: 10.7270/Q2SB481G
More data for this
Ligand-Target Pair