BDBM50238747 CHEMBL4064809

SMILES: Cl.COc1ccc(F)cc1C1CC1CNCc1ccccc1C#N

InChI Key: InChIKey=SEQKWVFOCJDPPW-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50238747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238747 (CHEMBL4064809) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNCc1ccccc1C#N Show InChI InChI=1S/C19H19FN2O.ClH/c1-23-19-7-6-16(20)9-18(19)17-8-15(17)12-22-11-14-5-3-2-4-13(14)10-21;/h2-7,9,15,17,22H,8,11-12H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	245	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at tTA containing TEV cleavage site-fused 5-HT2C-INI receptor isoform (unknown origin) expressed in TEV-fused beta-arrestin2 express...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238747 (CHEMBL4064809) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNCc1ccccc1C#N Show InChI InChI=1S/C19H19FN2O.ClH/c1-23-19-7-6-16(20)9-18(19)17-8-15(17)12-22-11-14-5-3-2-4-13(14)10-21;/h2-7,9,15,17,22H,8,11-12H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	721	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2A receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238747 (CHEMBL4064809) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNCc1ccccc1C#N Show InChI InChI=1S/C19H19FN2O.ClH/c1-23-19-7-6-16(20)9-18(19)17-8-15(17)12-22-11-14-5-3-2-4-13(14)10-21;/h2-7,9,15,17,22H,8,11-12H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	245	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C-INI receptor isoform expressed in Flp-IN HEK293 cells assessed as induction of Gq-mediated calcium flux measured eve...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238747 (CHEMBL4064809) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNCc1ccccc1C#N Show InChI InChI=1S/C19H19FN2O.ClH/c1-23-19-7-6-16(20)9-18(19)17-8-15(17)12-22-11-14-5-3-2-4-13(14)10-21;/h2-7,9,15,17,22H,8,11-12H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	238	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2B receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50238747 (CHEMBL4064809) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNCc1ccccc1C#N Show InChI InChI=1S/C19H19FN2O.ClH/c1-23-19-7-6-16(20)9-18(19)17-8-15(17)12-22-11-14-5-3-2-4-13(14)10-21;/h2-7,9,15,17,22H,8,11-12H2,1H3;1H	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2B receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238747 (CHEMBL4064809) Show SMILES Cl.COc1ccc(F)cc1C1CC1CNCc1ccccc1C#N Show InChI InChI=1S/C19H19FN2O.ClH/c1-23-19-7-6-16(20)9-18(19)17-8-15(17)12-22-11-14-5-3-2-4-13(14)10-21;/h2-7,9,15,17,22H,8,11-12H2,1H3;1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	724	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2A receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair