BDBM50238770 CHEMBL4104218

SMILES: Cl.COc1ccc(F)cc1[C@H]1C[C@@H]1CNCc1ccccc1Cl

InChI Key: InChIKey=GQHLQQKMSQROLY-PBCQUBLHSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50238770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238770 (CHEMBL4104218) Show SMILES Cl.COc1ccc(F)cc1[C@H]1C[C@@H]1CNCc1ccccc1Cl |r| Show InChI InChI=1S/C18H19ClFNO.ClH/c1-22-18-7-6-14(20)9-16(18)15-8-13(15)11-21-10-12-4-2-3-5-17(12)19;/h2-7,9,13,15,21H,8,10-11H2,1H3;1H/t13-,15+;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.55E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2A receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50238770 (CHEMBL4104218) Show SMILES Cl.COc1ccc(F)cc1[C@H]1C[C@@H]1CNCc1ccccc1Cl |r| Show InChI InChI=1S/C18H19ClFNO.ClH/c1-22-18-7-6-14(20)9-16(18)15-8-13(15)11-21-10-12-4-2-3-5-17(12)19;/h2-7,9,13,15,21H,8,10-11H2,1H3;1H/t13-,15+;/m1./s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2A receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by ...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238770 (CHEMBL4104218) Show SMILES Cl.COc1ccc(F)cc1[C@H]1C[C@@H]1CNCc1ccccc1Cl |r| Show InChI InChI=1S/C18H19ClFNO.ClH/c1-22-18-7-6-14(20)9-16(18)15-8-13(15)11-21-10-12-4-2-3-5-17(12)19;/h2-7,9,13,15,21H,8,10-11H2,1H3;1H/t13-,15+;/m1./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	529	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C-INI receptor isoform expressed in Flp-IN HEK293 cells assessed as induction of Gq-mediated calcium flux measured eve...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50238770 (CHEMBL4104218) Show SMILES Cl.COc1ccc(F)cc1[C@H]1C[C@@H]1CNCc1ccccc1Cl |r| Show InChI InChI=1S/C18H19ClFNO.ClH/c1-22-18-7-6-14(20)9-16(18)15-8-13(15)11-21-10-12-4-2-3-5-17(12)19;/h2-7,9,13,15,21H,8,10-11H2,1H3;1H/t13-,15+;/m1./s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	525	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C-INI receptor isoform expressed in Flp-IN HEK293 cells assessed as induction of Gq-mediated calcium flux measured eve...				J Med Chem 60: 6273-6288 (2017) Article DOI: 10.1021/acs.jmedchem.7b00584 BindingDB Entry DOI: 10.7270/Q2MK6G5C
					More data for this Ligand-Target Pair