BDBM50238938 CHEMBL4095241

SMILES: CC(C)(C)c1cccc(c1)-c1ccc(Oc2cccc(COc3ccccc3CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1

InChI Key: InChIKey=IEHHDCJODKNINL-UMSFTDKQSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50238938   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 34 (Mus musculus)	BDBM50238938 (CHEMBL4095241) Show SMILES CC(C)(C)c1cccc(c1)-c1ccc(Oc2cccc(COc3ccccc3CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1 |r| Show InChI InChI=1S/C38H44NO10P/c1-38(2,3)31-12-7-11-30(24-31)28-15-18-32(19-16-28)49-33-13-6-9-27(23-33)25-46-35-14-5-4-10-29(35)17-20-36(40)45-21-8-22-47-50(43,44)48-26-34(39)37(41)42/h4-7,9-16,18-19,23-24,34H,8,17,20-22,25-26,39H2,1-3H3,(H,41,42)(H,43,44)/t34-/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at mouse GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of ectodomain she...				J Med Chem 60: 6384-6399 (2017) Article DOI: 10.1021/acs.jmedchem.7b00693 BindingDB Entry DOI: 10.7270/Q2FX7CR1
					More data for this Ligand-Target Pair
G protein-coupled receptor 34 (Mus musculus)	BDBM50238938 (CHEMBL4095241) Show SMILES CC(C)(C)c1cccc(c1)-c1ccc(Oc2cccc(COc3ccccc3CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1 |r| Show InChI InChI=1S/C38H44NO10P/c1-38(2,3)31-12-7-11-30(24-31)28-15-18-32(19-16-28)49-33-13-6-9-27(23-33)25-46-35-14-5-4-10-29(35)17-20-36(40)45-21-8-22-47-50(43,44)48-26-34(39)37(41)42/h4-7,9-16,18-19,23-24,34H,8,17,20-22,25-26,39H2,1-3H3,(H,41,42)(H,43,44)/t34-/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description In vitro inhibitory activity against human plasma renin				J Med Chem 60: 6384-6399 (2017) Article DOI: 10.1021/acs.jmedchem.7b00693 BindingDB Entry DOI: 10.7270/Q2FX7CR1
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 34 (Homo sapiens (Human))	BDBM50238938 (CHEMBL4095241) Show SMILES CC(C)(C)c1cccc(c1)-c1ccc(Oc2cccc(COc3ccccc3CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1 |r| Show InChI InChI=1S/C38H44NO10P/c1-38(2,3)31-12-7-11-30(24-31)28-15-18-32(19-16-28)49-33-13-6-9-27(23-33)25-46-35-14-5-4-10-29(35)17-20-36(40)45-21-8-22-47-50(43,44)48-26-34(39)37(41)42/h4-7,9-16,18-19,23-24,34H,8,17,20-22,25-26,39H2,1-3H3,(H,41,42)(H,43,44)/t34-/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at human GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of AP-TGFalpha re...				J Med Chem 60: 6384-6399 (2017) Article DOI: 10.1021/acs.jmedchem.7b00693 BindingDB Entry DOI: 10.7270/Q2FX7CR1
					More data for this Ligand-Target Pair
Probable G-protein coupled receptor 34 (Homo sapiens (Human))	BDBM50238938 (CHEMBL4095241) Show SMILES CC(C)(C)c1cccc(c1)-c1ccc(Oc2cccc(COc3ccccc3CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c2)cc1 |r| Show InChI InChI=1S/C38H44NO10P/c1-38(2,3)31-12-7-11-30(24-31)28-15-18-32(19-16-28)49-33-13-6-9-27(23-33)25-46-35-14-5-4-10-29(35)17-20-36(40)45-21-8-22-47-50(43,44)48-26-34(39)37(41)42/h4-7,9-16,18-19,23-24,34H,8,17,20-22,25-26,39H2,1-3H3,(H,41,42)(H,43,44)/t34-/m0/s1	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Agonist activity at human GPR34 expressed in HEK293 cells co-transfected with AP-TGFalpha/chimeric Galphaq/i1 assessed as induction of AP-TGFalpha re...				J Med Chem 60: 6384-6399 (2017) Article DOI: 10.1021/acs.jmedchem.7b00693 BindingDB Entry DOI: 10.7270/Q2FX7CR1
					More data for this Ligand-Target Pair