BDBM50239365 CHEMBL4078747

SMILES: [H][C@]12C[C@@H](CO)N(C1)c1cc(Nc3cc4CCC(=O)N(CC5CC5)c4c(OC\C=C\CO2)c3)n2ncc(Cl)c2n1

InChI Key: InChIKey=CVYOHWBMGSIMET-AJLPNKGSSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239365   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
B-cell lymphoma 6 protein (Homo sapiens)	BDBM50239365 (CHEMBL4078747) Show SMILES [H][C@]12C[C@@H](CO)N(C1)c1cc(Nc3cc4CCC(=O)N(CC5CC5)c4c(OC\C=C\CO2)c3)n2ncc(Cl)c2n1 |r,t:31| Show InChI InChI=1S/C28H31ClN6O4/c29-22-13-30-35-25-12-24(32-28(22)35)33-15-21(11-20(33)16-36)38-7-1-2-8-39-23-10-19(31-25)9-18-5-6-26(37)34(27(18)23)14-17-3-4-17/h1-2,9-10,12-13,17,20-21,31,36H,3-8,11,14-16H2/b2-1+/t20-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of GAL4 DNA binding domain fused BCL6 BTB domain (unknown origin) expressed in HEK 293T/17 cells after 24 hrs by Bright-Glo luciferase cel...				J Med Chem 60: 4386-4402 (2017) Article DOI: 10.1021/acs.jmedchem.7b00359 BindingDB Entry DOI: 10.7270/Q2ZW1P1C
					More data for this Ligand-Target Pair
BCoR-BCL6 (Homo sapiens)	BDBM50239365 (CHEMBL4078747) Show SMILES [H][C@]12C[C@@H](CO)N(C1)c1cc(Nc3cc4CCC(=O)N(CC5CC5)c4c(OC\C=C\CO2)c3)n2ncc(Cl)c2n1 |r,t:31| Show InChI InChI=1S/C28H31ClN6O4/c29-22-13-30-35-25-12-24(32-28(22)35)33-15-21(11-20(33)16-36)38-7-1-2-8-39-23-10-19(31-25)9-18-5-6-26(37)34(27(18)23)14-17-3-4-17/h1-2,9-10,12-13,17,20-21,31,36H,3-8,11,14-16H2/b2-1+/t20-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of GAL4 DNA binding domain fused BCL6 BTB domain (unknown origin) expressed in HEK 293T/17 cells after 24 hrs by Bright-Glo luciferase cel...				J Med Chem 60: 4386-4402 (2017) Article DOI: 10.1021/acs.jmedchem.7b00359 BindingDB Entry DOI: 10.7270/Q2ZW1P1C
					More data for this Ligand-Target Pair
Zinc finger and BTB domain-containing protein 16 (Homo sapiens)	BDBM50239365 (CHEMBL4078747) Show SMILES [H][C@]12C[C@@H](CO)N(C1)c1cc(Nc3cc4CCC(=O)N(CC5CC5)c4c(OC\C=C\CO2)c3)n2ncc(Cl)c2n1 |r,t:31| Show InChI InChI=1S/C28H31ClN6O4/c29-22-13-30-35-25-12-24(32-28(22)35)33-15-21(11-20(33)16-36)38-7-1-2-8-39-23-10-19(31-25)9-18-5-6-26(37)34(27(18)23)14-17-3-4-17/h1-2,9-10,12-13,17,20-21,31,36H,3-8,11,14-16H2/b2-1+/t20-,21-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of GAL4 DNA binding domain fused PLZF BTB domain (unknown origin) expressed in HEK 293T/17 cells after 24 hrs by Bright-Glo luciferase cel...				J Med Chem 60: 4386-4402 (2017) Article DOI: 10.1021/acs.jmedchem.7b00359 BindingDB Entry DOI: 10.7270/Q2ZW1P1C
					More data for this Ligand-Target Pair