BDBM50239867 CHEMBL4070179

SMILES: O=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2ccccn2)c1

InChI Key: InChIKey=NZYWZQVSAMCCCA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50239867   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
U5 small nuclear ribonucleoprotein 200 kDa helicase (Homo sapiens (Human))	BDBM50239867 (CHEMBL4070179) Show SMILES O=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2ccccn2)c1 Show InChI InChI=1S/C26H22N4O3/c31-25-14-24-20(16-29(25)15-19-7-2-1-3-8-19)17-30(26(32)28-24)22-10-6-11-23(13-22)33-18-21-9-4-5-12-27-21/h1-14,16H,15,17-18H2,(H,28,32)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda California Inc. Curated by ChEMBL					Assay Description Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...				J Med Chem 60: 5759-5771 (2017) Article DOI: 10.1021/acs.jmedchem.7b00461 BindingDB Entry DOI: 10.7270/Q2MC925G
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