BDBM50240583 CHEMBL4085712

SMILES: COc1cc(OC)c(F)c(COc2cnc(N[C@@H]3CCCC[C@@H]3NC(=O)C=C)nc2)c1F

InChI Key: InChIKey=IGOFQHGDEGZDKJ-JKSUJKDBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM50240583 (CHEMBL4085712) Show SMILES COc1cc(OC)c(F)c(COc2cnc(N[C@@H]3CCCC[C@@H]3NC(=O)C=C)nc2)c1F |r| Show InChI InChI=1S/C22H26F2N4O4/c1-4-19(29)27-15-7-5-6-8-16(15)28-22-25-10-13(11-26-22)32-12-14-20(23)17(30-2)9-18(31-3)21(14)24/h4,9-11,15-16H,1,5-8,12H2,2-3H3,(H,27,29)(H,25,26,28)/t15-,16+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
WuXi AppTec (Shanghai) Co., Ltd. Curated by ChEMBL					Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex				Bioorg Med Chem Lett 27: 2420-2423 (2017) Article DOI: 10.1016/j.bmcl.2017.04.014 BindingDB Entry DOI: 10.7270/Q2M90BT6
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50240583 (CHEMBL4085712) Show SMILES COc1cc(OC)c(F)c(COc2cnc(N[C@@H]3CCCC[C@@H]3NC(=O)C=C)nc2)c1F |r| Show InChI InChI=1S/C22H26F2N4O4/c1-4-19(29)27-15-7-5-6-8-16(15)28-22-25-10-13(11-26-22)32-12-14-20(23)17(30-2)9-18(31-3)21(14)24/h4,9-11,15-16H,1,5-8,12H2,2-3H3,(H,27,29)(H,25,26,28)/t15-,16+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
WuXi AppTec (Shanghai) Co., Ltd. Curated by ChEMBL					Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex				Bioorg Med Chem Lett 27: 2420-2423 (2017) Article DOI: 10.1016/j.bmcl.2017.04.014 BindingDB Entry DOI: 10.7270/Q2M90BT6
					More data for this Ligand-Target Pair