BDBM50240584 CHEMBL4073517

SMILES: COc1cc(OC)c(F)c(COc2cnc(N[C@@H]3COCC[C@@H]3NC(=O)C=C)nc2)c1F

InChI Key: InChIKey=INDPOZGXJZSNRO-LSDHHAIUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240584   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM50240584 (CHEMBL4073517) Show SMILES COc1cc(OC)c(F)c(COc2cnc(N[C@@H]3COCC[C@@H]3NC(=O)C=C)nc2)c1F |r| Show InChI InChI=1S/C21H24F2N4O5/c1-4-18(28)26-14-5-6-31-11-15(14)27-21-24-8-12(9-25-21)32-10-13-19(22)16(29-2)7-17(30-3)20(13)23/h4,7-9,14-15H,1,5-6,10-11H2,2-3H3,(H,26,28)(H,24,25,27)/t14-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	148	n/a	n/a	n/a	n/a	n/a	n/a
WuXi AppTec (Shanghai) Co., Ltd. Curated by ChEMBL					Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex				Bioorg Med Chem Lett 27: 2420-2423 (2017) Article DOI: 10.1016/j.bmcl.2017.04.014 BindingDB Entry DOI: 10.7270/Q2M90BT6
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50240584 (CHEMBL4073517) Show SMILES COc1cc(OC)c(F)c(COc2cnc(N[C@@H]3COCC[C@@H]3NC(=O)C=C)nc2)c1F |r| Show InChI InChI=1S/C21H24F2N4O5/c1-4-18(28)26-14-5-6-31-11-15(14)27-21-24-8-12(9-25-21)32-10-13-19(22)16(29-2)7-17(30-3)20(13)23/h4,7-9,14-15H,1,5-6,10-11H2,2-3H3,(H,26,28)(H,24,25,27)/t14-,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
WuXi AppTec (Shanghai) Co., Ltd. Curated by ChEMBL					Assay Description Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortex				Bioorg Med Chem Lett 27: 2420-2423 (2017) Article DOI: 10.1016/j.bmcl.2017.04.014 BindingDB Entry DOI: 10.7270/Q2M90BT6
					More data for this Ligand-Target Pair