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SMILES: Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccccc1CO

InChI Key: InChIKey=IBIHVAILDLNSJB-MHZLTWQESA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240766   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50240766
PNG
(CHEMBL4084547)
Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccccc1CO |r|
Show InChI InChI=1S/C28H26N4O2/c1-18-24-13-20(11-12-26(24)32-31-18)25-14-22(30-27(17-34)19-7-3-2-4-8-19)15-29-28(25)23-10-6-5-9-21(23)16-33/h2-15,27,30,33-34H,16-17H2,1H3,(H,31,32)/t27-/m0/s1
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Article
PubMed
n/an/a 167n/an/an/an/an/an/a



University of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA


J Med Chem 60: 6018-6035 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM50240766
PNG
(CHEMBL4084547)
Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccccc1CO |r|
Show InChI InChI=1S/C28H26N4O2/c1-18-24-13-20(11-12-26(24)32-31-18)25-14-22(30-27(17-34)19-7-3-2-4-8-19)15-29-28(25)23-10-6-5-9-21(23)16-33/h2-15,27,30,33-34H,16-17H2,1H3,(H,31,32)/t27-/m0/s1
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Article
PubMed
n/an/a 251n/an/an/an/an/an/a



University of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA


J Med Chem 60: 6018-6035 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM50240766
PNG
(CHEMBL4084547)
Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1ccccc1CO |r|
Show InChI InChI=1S/C28H26N4O2/c1-18-24-13-20(11-12-26(24)32-31-18)25-14-22(30-27(17-34)19-7-3-2-4-8-19)15-29-28(25)23-10-6-5-9-21(23)16-33/h2-15,27,30,33-34H,16-17H2,1H3,(H,31,32)/t27-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 51n/an/an/an/an/an/a



University of Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA


J Med Chem 60: 6018-6035 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC
More data for this
Ligand-Target Pair