BDBM50240786 CHEMBL4102355

SMILES: CC(C)c1ccc(O)c(c1)-c1ncc(N[C@@H](CO)c2ccccc2)cc1-c1ccc2[nH]nc(C)c2c1

InChI Key: InChIKey=PGLVHGMGVZWTEO-NDEPHWFRSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50240786 (CHEMBL4102355) Show SMILES CC(C)c1ccc(O)c(c1)-c1ncc(N[C@@H](CO)c2ccccc2)cc1-c1ccc2[nH]nc(C)c2c1 |r| Show InChI InChI=1S/C30H30N4O2/c1-18(2)21-10-12-29(36)26(13-21)30-25(22-9-11-27-24(14-22)19(3)33-34-27)15-23(16-31-30)32-28(17-35)20-7-5-4-6-8-20/h4-16,18,28,32,35-36H,17H2,1-3H3,(H,33,34)/t28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50240786 (CHEMBL4102355) Show SMILES CC(C)c1ccc(O)c(c1)-c1ncc(N[C@@H](CO)c2ccccc2)cc1-c1ccc2[nH]nc(C)c2c1 |r| Show InChI InChI=1S/C30H30N4O2/c1-18(2)21-10-12-29(36)26(13-21)30-25(22-9-11-27-24(14-22)19(3)33-34-27)15-23(16-31-30)32-28(17-35)20-7-5-4-6-8-20/h4-16,18,28,32,35-36H,17H2,1-3H3,(H,33,34)/t28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50240786 (CHEMBL4102355) Show SMILES CC(C)c1ccc(O)c(c1)-c1ncc(N[C@@H](CO)c2ccccc2)cc1-c1ccc2[nH]nc(C)c2c1 |r| Show InChI InChI=1S/C30H30N4O2/c1-18(2)21-10-12-29(36)26(13-21)30-25(22-9-11-27-24(14-22)19(3)33-34-27)15-23(16-31-30)32-28(17-35)20-7-5-4-6-8-20/h4-16,18,28,32,35-36H,17H2,1-3H3,(H,33,34)/t28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair