BDBM50240791 CHEMBL4077119

SMILES: OC[C@H](Nc1cnc(-c2cc(Cl)ccc2O)c(c1)-c1ccc2NC(=O)Cc2c1)c1ccccc1

InChI Key: InChIKey=NGVJHXBKRDWBLJ-DEOSSOPVSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50240791 (CHEMBL4077119) Show SMILES OC[C@H](Nc1cnc(-c2cc(Cl)ccc2O)c(c1)-c1ccc2NC(=O)Cc2c1)c1ccccc1 |r| Show InChI InChI=1S/C27H22ClN3O3/c28-19-7-9-25(33)22(12-19)27-21(17-6-8-23-18(10-17)11-26(34)31-23)13-20(14-29-27)30-24(15-32)16-4-2-1-3-5-16/h1-10,12-14,24,30,32-33H,11,15H2,(H,31,34)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	592	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50240791 (CHEMBL4077119) Show SMILES OC[C@H](Nc1cnc(-c2cc(Cl)ccc2O)c(c1)-c1ccc2NC(=O)Cc2c1)c1ccccc1 |r| Show InChI InChI=1S/C27H22ClN3O3/c28-19-7-9-25(33)22(12-19)27-21(17-6-8-23-18(10-17)11-26(34)31-23)13-20(14-29-27)30-24(15-32)16-4-2-1-3-5-16/h1-10,12-14,24,30,32-33H,11,15H2,(H,31,34)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50240791 (CHEMBL4077119) Show SMILES OC[C@H](Nc1cnc(-c2cc(Cl)ccc2O)c(c1)-c1ccc2NC(=O)Cc2c1)c1ccccc1 |r| Show InChI InChI=1S/C27H22ClN3O3/c28-19-7-9-25(33)22(12-19)27-21(17-6-8-23-18(10-17)11-26(34)31-23)13-20(14-29-27)30-24(15-32)16-4-2-1-3-5-16/h1-10,12-14,24,30,32-33H,11,15H2,(H,31,34)/t24-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair