null

SMILES: CC(=O)Nc1ccc(cc1)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(Cl)ccc1O

InChI Key: InChIKey=TVDNYIBSQOHOJK-VWLOTQADSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50240792 (CHEMBL4063010) Show SMILES CC(=O)Nc1ccc(cc1)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(Cl)ccc1O |r| Show InChI InChI=1S/C27H24ClN3O3/c1-17(33)30-21-10-7-18(8-11-21)23-14-22(31-25(16-32)19-5-3-2-4-6-19)15-29-27(23)24-13-20(28)9-12-26(24)34/h2-15,25,31-32,34H,16H2,1H3,(H,30,33)/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50240792 (CHEMBL4063010) Show SMILES CC(=O)Nc1ccc(cc1)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(Cl)ccc1O |r| Show InChI InChI=1S/C27H24ClN3O3/c1-17(33)30-21-10-7-18(8-11-21)23-14-22(31-25(16-32)19-5-3-2-4-6-19)15-29-27(23)24-13-20(28)9-12-26(24)34/h2-15,25,31-32,34H,16H2,1H3,(H,30,33)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50240792 (CHEMBL4063010) Show SMILES CC(=O)Nc1ccc(cc1)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(Cl)ccc1O |r| Show InChI InChI=1S/C27H24ClN3O3/c1-17(33)30-21-10-7-18(8-11-21)23-14-22(31-25(16-32)19-5-3-2-4-6-19)15-29-27(23)24-13-20(28)9-12-26(24)34/h2-15,25,31-32,34H,16H2,1H3,(H,30,33)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA				J Med Chem 60: 6018-6035 (2017) Article DOI: 10.1021/acs.jmedchem.7b00076 BindingDB Entry DOI: 10.7270/Q2K939NC
					More data for this Ligand-Target Pair