BDBM50241028 1-Isopropyl-1H-benzotriazole-5-carboxylic acid::1-isopropyl-benzotraizole-5-carboxylic acid::CHEMBL381638

SMILES: CC(C)n1nnc2cc(ccc12)C(O)=O

InChI Key: InChIKey=RUTVRAJKELSHCC-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HM74 nicotinic acid GPCR (Homo sapiens (Human))	BDBM50241028 (1-Isopropyl-1H-benzotriazole-5-carboxylic acid | 1...) Show SMILES CC(C)n1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C10H11N3O2/c1-6(2)13-9-4-3-7(10(14)15)5-8(9)11-12-13/h3-6H,1-2H3,(H,14,15)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50241028 (1-Isopropyl-1H-benzotriazole-5-carboxylic acid | 1...) Show SMILES CC(C)n1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C10H11N3O2/c1-6(2)13-9-4-3-7(10(14)15)5-8(9)11-12-13/h3-6H,1-2H3,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Activity at GPR109a (unknown origin) assessed as inhibition of forskolin-stimulated cAMP production				J Med Chem 51: 7653-62 (2008) Article DOI: 10.1021/jm800896z BindingDB Entry DOI: 10.7270/Q27D2TZ5
					More data for this Ligand-Target Pair