BDBM50241185 (E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-hydroxyphenyl)acrylamide::CHEMBL242867::N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-hydroxyphenyl)acrylamide

SMILES: CC(C)(NC(=O)\C=C\c1ccc(O)cc1)C(=O)NCCc1c[nH]c2ccccc12

InChI Key: InChIKey=TXILOVGTDLDQDB-FMIVXFBMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50241185 ((E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-...) Show SMILES CC(C)(NC(=O)\C=C\c1ccc(O)cc1)C(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C23H25N3O3/c1-23(2,26-21(28)12-9-16-7-10-18(27)11-8-16)22(29)24-14-13-17-15-25-20-6-4-3-5-19(17)20/h3-12,15,25,27H,13-14H2,1-2H3,(H,24,29)(H,26,28)/b12-9+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of SIRT2				Bioorg Med Chem Lett 17: 2448-51 (2007) Article DOI: 10.1016/j.bmcl.2007.02.023 BindingDB Entry DOI: 10.7270/Q2CR5V53
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50241185 ((E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-...) Show SMILES CC(C)(NC(=O)\C=C\c1ccc(O)cc1)C(=O)NCCc1c[nH]c2ccccc12 Show InChI InChI=1S/C23H25N3O3/c1-23(2,26-21(28)12-9-16-7-10-18(27)11-8-16)22(29)24-14-13-17-15-25-20-6-4-3-5-19(17)20/h3-12,15,25,27H,13-14H2,1-2H3,(H,24,29)(H,26,28)/b12-9+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged SIRT2 (unknown origin) by Fluor de Lys fluorescence assay				Bioorg Med Chem 16: 8054-62 (2008) Article DOI: 10.1016/j.bmc.2008.07.059 BindingDB Entry DOI: 10.7270/Q2TB16QS
					More data for this Ligand-Target Pair