null

SMILES: CC(C)(NC(=O)\C=C\c1ccc(O)cc1)C(=O)NCCc1c[nH]c2ccc(F)cc12

InChI Key: InChIKey=PPZLXJZWCDRKEV-BJMVGYQFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50241187 ((E)-N-(1-(2-(5-fluoro-1H-indol-3-yl)ethylamino)-2-...) Show SMILES CC(C)(NC(=O)\C=C\c1ccc(O)cc1)C(=O)NCCc1c[nH]c2ccc(F)cc12 Show InChI InChI=1S/C23H24FN3O3/c1-23(2,27-21(29)10-5-15-3-7-18(28)8-4-15)22(30)25-12-11-16-14-26-20-9-6-17(24)13-19(16)20/h3-10,13-14,26,28H,11-12H2,1-2H3,(H,25,30)(H,27,29)/b10-5+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of SIRT2				Bioorg Med Chem Lett 17: 2448-51 (2007) Article DOI: 10.1016/j.bmcl.2007.02.023 BindingDB Entry DOI: 10.7270/Q2CR5V53
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50241187 ((E)-N-(1-(2-(5-fluoro-1H-indol-3-yl)ethylamino)-2-...) Show SMILES CC(C)(NC(=O)\C=C\c1ccc(O)cc1)C(=O)NCCc1c[nH]c2ccc(F)cc12 Show InChI InChI=1S/C23H24FN3O3/c1-23(2,27-21(29)10-5-15-3-7-18(28)8-4-15)22(30)25-12-11-16-14-26-20-9-6-17(24)13-19(16)20/h3-10,13-14,26,28H,11-12H2,1-2H3,(H,25,30)(H,27,29)/b10-5+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged SIRT2 (unknown origin) by Fluor de Lys fluorescence assay				Bioorg Med Chem 16: 8054-62 (2008) Article DOI: 10.1016/j.bmc.2008.07.059 BindingDB Entry DOI: 10.7270/Q2TB16QS
					More data for this Ligand-Target Pair