BDBM50241204 (E)-3-(4-(benzyloxy)phenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one::4-benzyloxy-2'-hydroxychalcone::CHEMBL242078

SMILES: Oc1ccccc1C(=O)\C=C\c1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=PQZKTWBQDPHGOU-NTCAYCPXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50241204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-2 (COX-2) (Mus musculus (Mouse))	BDBM50241204 ((E)-3-(4-(benzyloxy)phenyl)-1-(2-hydroxyphenyl)pro...) Show SMILES Oc1ccccc1C(=O)\C=C\c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C22H18O3/c23-21-9-5-4-8-20(21)22(24)15-12-17-10-13-19(14-11-17)25-16-18-6-2-1-3-7-18/h1-15,23H,16H2/b15-12+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Medicine and Pharmacy at Ho Chi Minh City Curated by ChEMBL					Assay Description Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassay				Bioorg Med Chem Lett 19: 1650-3 (2009) Article DOI: 10.1016/j.bmcl.2009.02.001 BindingDB Entry DOI: 10.7270/Q28052HJ
					More data for this Ligand-Target Pair