BDBM50241309 1-(3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-propoxyphenylsulfonyl)piperidin-4-ylphosphonic acid::CHEMBL245922::{1-[3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-propoxy-benzenesulfonyl]-piperidin-4-yl}-phosphonic acid

SMILES: CCCOc1ccc(cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1)S(=O)(=O)N1CCC(CC1)P(O)(O)=O

InChI Key: InChIKey=UVGITDAEOIEWAN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50241309 (1-(3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyraz...) Show SMILES CCCOc1ccc(cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1)S(=O)(=O)N1CCC(CC1)P(O)(O)=O Show InChI InChI=1S/C23H32N5O7PS/c1-4-6-18-20-21(27(3)26-18)23(29)25-22(24-20)17-14-16(7-8-19(17)35-13-5-2)37(33,34)28-11-9-15(10-12-28)36(30,31)32/h7-8,14-15H,4-6,9-13H2,1-3H3,(H,24,25,29)(H2,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.708	n/a	n/a	n/a	n/a	n/a	n/a
Sungkyunkwan University Curated by ChEMBL					Assay Description Inhibition of PDE5				Bioorg Med Chem Lett 17: 4271-4 (2007) Article DOI: 10.1016/j.bmcl.2007.05.064 BindingDB Entry DOI: 10.7270/Q289172C
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50241309 (1-(3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyraz...) Show SMILES CCCOc1ccc(cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1)S(=O)(=O)N1CCC(CC1)P(O)(O)=O Show InChI InChI=1S/C23H32N5O7PS/c1-4-6-18-20-21(27(3)26-18)23(29)25-22(24-20)17-14-16(7-8-19(17)35-13-5-2)37(33,34)28-11-9-15(10-12-28)36(30,31)32/h7-8,14-15H,4-6,9-13H2,1-3H3,(H,24,25,29)(H2,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Ewha Womans University Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 5 of rabbit platelets				Bioorg Med Chem Lett 14: 2099-103 (2004) Article DOI: 10.1016/j.bmcl.2004.02.040 BindingDB Entry DOI: 10.7270/Q290237J
					More data for this Ligand-Target Pair