BDBM50241581 CHEMBL4079161

SMILES: O\N=c1/cc(oc2ccccc12)-c1cc2sccc2cn1

InChI Key: InChIKey=HNAMZQHQZIBIFK-LDADJPATSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50241581   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50241581 (CHEMBL4079161) Show SMILES O\N=c1/cc(oc2ccccc12)-c1cc2sccc2cn1 Show InChI InChI=1S/C16H10N2O2S/c19-18-12-7-15(20-14-4-2-1-3-11(12)14)13-8-16-10(9-17-13)5-6-21-16/h1-9,19H/b18-12+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Prexton Therapeutics Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...				J Med Chem 60: 8515-8537 (2017) Article DOI: 10.1021/acs.jmedchem.7b00991 BindingDB Entry DOI: 10.7270/Q2GF0WNQ
					More data for this Ligand-Target Pair