BDBM50241728 CHEMBL4103618

SMILES: Fc1cccc(Cl)c1CNc1nc(n[nH]1)-c1ccccc1

InChI Key: InChIKey=YFJVZDLGOGONKG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50241728   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241728 (CHEMBL4103618) Show SMILES Fc1cccc(Cl)c1CNc1nc(n[nH]1)-c1ccccc1 Show InChI InChI=1S/C15H12ClFN4/c16-12-7-4-8-13(17)11(12)9-18-15-19-14(20-21-15)10-5-2-1-3-6-10/h1-8H,9H2,(H2,18,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Biological Sciences, Beijing Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8552-8564 (2017) Article DOI: 10.1021/acs.jmedchem.7b01075 BindingDB Entry DOI: 10.7270/Q25X2C34
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50241728 (CHEMBL4103618) Show SMILES Fc1cccc(Cl)c1CNc1nc(n[nH]1)-c1ccccc1 Show InChI InChI=1S/C15H12ClFN4/c16-12-7-4-8-13(17)11(12)9-18-15-19-14(20-21-15)10-5-2-1-3-6-10/h1-8H,9H2,(H2,18,19,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	468	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Biological Sciences, Beijing Curated by ChEMBL					Assay Description Inhibition of His-tagged full length recombinant human LCK expressed in baculovirus expression system using TK-substrate-biotin after 40 mins by HTRF...				J Med Chem 60: 8552-8564 (2017) Article DOI: 10.1021/acs.jmedchem.7b01075 BindingDB Entry DOI: 10.7270/Q25X2C34
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50241728 (CHEMBL4103618) Show SMILES Fc1cccc(Cl)c1CNc1nc(n[nH]1)-c1ccccc1 Show InChI InChI=1S/C15H12ClFN4/c16-12-7-4-8-13(17)11(12)9-18-15-19-14(20-21-15)10-5-2-1-3-6-10/h1-8H,9H2,(H2,18,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Biological Sciences, Beijing Curated by ChEMBL					Assay Description The compound was tested for the inhibition of fibrinogen receptor				J Med Chem 60: 8552-8564 (2017) Article DOI: 10.1021/acs.jmedchem.7b01075 BindingDB Entry DOI: 10.7270/Q25X2C34
					More data for this Ligand-Target Pair