BDBM50241730 CHEMBL4100228

SMILES: Nc1cccc(c1)-c1n[nH]c(NCc2c(F)cccc2Cl)n1

InChI Key: InChIKey=SHCJFEFQZWRVRD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50241730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241730 (CHEMBL4100228) Show SMILES Nc1cccc(c1)-c1n[nH]c(NCc2c(F)cccc2Cl)n1 Show InChI InChI=1S/C15H13ClFN5/c16-12-5-2-6-13(17)11(12)8-19-15-20-14(21-22-15)9-3-1-4-10(18)7-9/h1-7H,8,18H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Biological Sciences, Beijing Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8552-8564 (2017) Article DOI: 10.1021/acs.jmedchem.7b01075 BindingDB Entry DOI: 10.7270/Q25X2C34
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50241730 (CHEMBL4100228) Show SMILES Nc1cccc(c1)-c1n[nH]c(NCc2c(F)cccc2Cl)n1 Show InChI InChI=1S/C15H13ClFN5/c16-12-5-2-6-13(17)11(12)8-19-15-20-14(21-22-15)9-3-1-4-10(18)7-9/h1-7H,8,18H2,(H2,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	526	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Biological Sciences, Beijing Curated by ChEMBL					Assay Description Inhibition of Fibrinogen binding to Fibrinogen receptor				J Med Chem 60: 8552-8564 (2017) Article DOI: 10.1021/acs.jmedchem.7b01075 BindingDB Entry DOI: 10.7270/Q25X2C34
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50241730 (CHEMBL4100228) Show SMILES Nc1cccc(c1)-c1n[nH]c(NCc2c(F)cccc2Cl)n1 Show InChI InChI=1S/C15H13ClFN5/c16-12-5-2-6-13(17)11(12)8-19-15-20-14(21-22-15)9-3-1-4-10(18)7-9/h1-7H,8,18H2,(H2,19,20,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Biological Sciences, Beijing Curated by ChEMBL					Assay Description Inhibition of ADP-induced platelet aggregation in human platelet-rich plasma				J Med Chem 60: 8552-8564 (2017) Article DOI: 10.1021/acs.jmedchem.7b01075 BindingDB Entry DOI: 10.7270/Q25X2C34
					More data for this Ligand-Target Pair