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SMILES: CC(C)(C)c1ccc(cc1)-c1cc(no1)C(=O)C(=N\Nc1cccc(Cl)c1)\C#N

InChI Key: InChIKey=UCZLCCZFNICGRG-LGUFXXKBSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50241951   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rap guanine nucleotide exchange factor 3


(Homo sapiens (Human))		BDBM50241951
PNG
(CHEMBL4092801)
Show SMILES CC(C)(C)c1ccc(cc1)-c1cc(no1)C(=O)C(=N\Nc1cccc(Cl)c1)\C#N
Show InChI InChI=1S/C22H19ClN4O2/c1-22(2,3)15-9-7-14(8-10-15)20-12-18(27-29-20)21(28)19(13-24)26-25-17-6-4-5-16(23)11-17/h4-12,25H,1-3H3/b26-19+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.60E+3n/an/an/an/an/an/a



University of Texas Medical Branch

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...

Eur J Med Chem 134: 62-71 (2017)


Article DOI: 10.1016/j.ejmech.2017.04.001
BindingDB Entry DOI: 10.7270/Q2RR21DK
More data for this
Ligand-Target Pair