BDBM50241960 CHEMBL4061233

SMILES: Fc1ccc(N\N=C(/C#N)C(=O)c2noc3ccccc23)cc1Cl

InChI Key: InChIKey=XLPHDYVUBGODSJ-FYJGNVAPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50241960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 3 (Homo sapiens (Human))	BDBM50241960 (CHEMBL4061233) Show SMILES Fc1ccc(N\N=C(/C#N)C(=O)c2noc3ccccc23)cc1Cl Show InChI InChI=1S/C16H8ClFN4O2/c17-11-7-9(5-6-12(11)18)20-21-13(8-19)16(23)15-10-3-1-2-4-14(10)24-22-15/h1-7,20H/b21-13+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description In vito concentration required to displace [3H]-BRM (Kd = 1.0 nM and concentration is 1.8 nM) from opioid receptor kappa 2 in guinea brain membranes.				Eur J Med Chem 134: 62-71 (2017) Article DOI: 10.1016/j.ejmech.2017.04.001 BindingDB Entry DOI: 10.7270/Q2RR21DK
					More data for this Ligand-Target Pair