BDBM50241970 CHEMBL4070928

SMILES: Clc1cccc(N\N=C(/C#N)C(=O)c2noc3ccccc23)c1

InChI Key: InChIKey=LSNGOAPDLGIVAZ-DEDYPNTBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50241970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 3 (Homo sapiens (Human))	BDBM50241970 (CHEMBL4070928) Show SMILES Clc1cccc(N\N=C(/C#N)C(=O)c2noc3ccccc23)c1 Show InChI InChI=1S/C16H9ClN4O2/c17-10-4-3-5-11(8-10)19-20-13(9-18)16(22)15-12-6-1-2-7-14(12)23-21-15/h1-8,19H/b20-13+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...				Eur J Med Chem 134: 62-71 (2017) Article DOI: 10.1016/j.ejmech.2017.04.001 BindingDB Entry DOI: 10.7270/Q2RR21DK
					More data for this Ligand-Target Pair