BDBM50242657 CHEMBL4104938

SMILES: CC(C)(C)OC(=O)N1CCN(CC1)C(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O

InChI Key: InChIKey=BSVITRQUFSAGJN-FPLPWBNLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50242657 (CHEMBL4104938) Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)C(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C20H26N4O5/c1-20(2,3)29-19(28)24-11-9-23(10-12-24)17(26)8-7-16(25)22-15-6-4-5-14(13-15)18(21)27/h4-8,13H,9-12H2,1-3H3,(H2,21,27)(H,22,25)/b8-7-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50242657 (CHEMBL4104938) Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)C(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C20H26N4O5/c1-20(2,3)29-19(28)24-11-9-23(10-12-24)17(26)8-7-16(25)22-15-6-4-5-14(13-15)18(21)27/h4-8,13H,9-12H2,1-3H3,(H2,21,27)(H,22,25)/b8-7-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	372	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair