BDBM50242941 2-Furan-2-yl-7-[2-(3-phenyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-ethyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine::CHEMBL469879

SMILES: Nc1nc2n(CCN3CCc4ncc(cc4C3)-c3ccccc3)ncc2c2nc(nn12)-c1ccco1

InChI Key: InChIKey=STSFNYOXZHOPBF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50242941 (2-Furan-2-yl-7-[2-(3-phenyl-7,8-dihydro-5H-[1,6]na...) Show SMILES Nc1nc2n(CCN3CCc4ncc(cc4C3)-c3ccccc3)ncc2c2nc(nn12)-c1ccco1 Show InChI InChI=1S/C26H23N9O/c27-26-31-24-20(25-30-23(32-35(25)26)22-7-4-12-36-22)15-29-34(24)11-10-33-9-8-21-19(16-33)13-18(14-28-21)17-5-2-1-3-6-17/h1-7,12-15H,8-11,16H2,(H2,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	17.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human adenosine A2A receptor				Bioorg Med Chem Lett 18: 4204-9 (2008) Article DOI: 10.1016/j.bmcl.2008.05.069 BindingDB Entry DOI: 10.7270/Q2JS9Q7R
					More data for this Ligand-Target Pair