null

SMILES: COc1ccc(NC(=O)c2cc(O)cc(O)c2)cc1

InChI Key: InChIKey=VXUIVOFEVWOPJE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50243349 (CHEMBL4090371) Show SMILES COc1ccc(NC(=O)c2cc(O)cc(O)c2)cc1 Show InChI InChI=1S/C14H13NO4/c1-19-13-4-2-10(3-5-13)15-14(18)9-6-11(16)8-12(17)7-9/h2-8,16-17H,1H3,(H,15,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hyogo University of Health Sciences Curated by ChEMBL					Assay Description Inhibition of human TRPA1 expressed in HEK293 cells assessed as decrease in AITC-induced calcium influx preincubated for 6 mins followed by AITC addi...				Bioorg Med Chem Lett 27: 3167-3172 (2017) Article DOI: 10.1016/j.bmcl.2017.05.025 BindingDB Entry DOI: 10.7270/Q2TH8Q4R
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50243349 (CHEMBL4090371) Show SMILES COc1ccc(NC(=O)c2cc(O)cc(O)c2)cc1 Show InChI InChI=1S/C14H13NO4/c1-19-13-4-2-10(3-5-13)15-14(18)9-6-11(16)8-12(17)7-9/h2-8,16-17H,1H3,(H,15,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Hyogo University of Health Sciences Curated by ChEMBL					Assay Description Agonist activity at human TRPA1 expressed in HEK293 cells assessed as induction of calcium influx at 30 uM after 6 mins by Fluo-4 dye-based assay				Bioorg Med Chem Lett 27: 3167-3172 (2017) Article DOI: 10.1016/j.bmcl.2017.05.025 BindingDB Entry DOI: 10.7270/Q2TH8Q4R
					More data for this Ligand-Target Pair