BDBM50243515 (2R)-2-amino-N-[(4R,7S,10S,13R,16S,19S)-10-(4-aminobutyl)-4-{[(1S)-1-carbamoyl-2-(naphthalen-2-yl)ethyl]carbamoyl}-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]-3-(4-chlorophenyl)propanamide::CHEMBL510755

SMILES: C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@H](N)Cc1ccc(Cl)cc1

InChI Key: InChIKey=KYHOGWCSGFSFNN-PUADLLEESA-N

Data: 3 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50243515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50243515 ((2R)-2-amino-N-[(4R,7S,10S,13R,16S,19S)-10-(4-amin...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C58H68ClN11O10S2/c1-32(71)50-58(80)69-49(56(78)65-45(51(62)73)27-35-13-18-36-8-2-3-9-37(36)24-35)31-82-81-30-48(68-52(74)42(61)25-33-14-19-39(59)20-15-33)57(79)66-46(26-34-16-21-40(72)22-17-34)54(76)67-47(28-38-29-63-43-11-5-4-10-41(38)43)55(77)64-44(53(75)70-50)12-6-7-23-60/h2-5,8-11,13-22,24,29,32,42,44-50,63,71-72H,6-7,12,23,25-28,30-31,60-61H2,1H3,(H2,62,73)(H,64,77)(H,65,78)(H,66,79)(H,67,76)(H,68,74)(H,69,80)(H,70,75)/t32-,42-,44+,45+,46+,47-,48-,49+,50+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Binding affinity to human cloned sst2 receptor				J Med Chem 51: 4030-7 (2008) Article DOI: 10.1021/jm701618q BindingDB Entry DOI: 10.7270/Q22J6CSW
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50243515 ((2R)-2-amino-N-[(4R,7S,10S,13R,16S,19S)-10-(4-amin...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C58H68ClN11O10S2/c1-32(71)50-58(80)69-49(56(78)65-45(51(62)73)27-35-13-18-36-8-2-3-9-37(36)24-35)31-82-81-30-48(68-52(74)42(61)25-33-14-19-39(59)20-15-33)57(79)66-46(26-34-16-21-40(72)22-17-34)54(76)67-47(28-38-29-63-43-11-5-4-10-41(38)43)55(77)64-44(53(75)70-50)12-6-7-23-60/h2-5,8-11,13-22,24,29,32,42,44-50,63,71-72H,6-7,12,23,25-28,30-31,60-61H2,1H3,(H2,62,73)(H,64,77)(H,65,78)(H,66,79)(H,67,76)(H,68,74)(H,69,80)(H,70,75)/t32-,42-,44+,45+,46+,47-,48-,49+,50+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Binding affinity to human cloned sst5 receptor				J Med Chem 51: 4030-7 (2008) Article DOI: 10.1021/jm701618q BindingDB Entry DOI: 10.7270/Q22J6CSW
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50243515 ((2R)-2-amino-N-[(4R,7S,10S,13R,16S,19S)-10-(4-amin...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C58H68ClN11O10S2/c1-32(71)50-58(80)69-49(56(78)65-45(51(62)73)27-35-13-18-36-8-2-3-9-37(36)24-35)31-82-81-30-48(68-52(74)42(61)25-33-14-19-39(59)20-15-33)57(79)66-46(26-34-16-21-40(72)22-17-34)54(76)67-47(28-38-29-63-43-11-5-4-10-41(38)43)55(77)64-44(53(75)70-50)12-6-7-23-60/h2-5,8-11,13-22,24,29,32,42,44-50,63,71-72H,6-7,12,23,25-28,30-31,60-61H2,1H3,(H2,62,73)(H,64,77)(H,65,78)(H,66,79)(H,67,76)(H,68,74)(H,69,80)(H,70,75)/t32-,42-,44+,45+,46+,47-,48-,49+,50+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Binding affinity to human cloned sst3 receptor				J Med Chem 51: 4030-7 (2008) Article DOI: 10.1021/jm701618q BindingDB Entry DOI: 10.7270/Q22J6CSW
					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50243515 ((2R)-2-amino-N-[(4R,7S,10S,13R,16S,19S)-10-(4-amin...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C58H68ClN11O10S2/c1-32(71)50-58(80)69-49(56(78)65-45(51(62)73)27-35-13-18-36-8-2-3-9-37(36)24-35)31-82-81-30-48(68-52(74)42(61)25-33-14-19-39(59)20-15-33)57(79)66-46(26-34-16-21-40(72)22-17-34)54(76)67-47(28-38-29-63-43-11-5-4-10-41(38)43)55(77)64-44(53(75)70-50)12-6-7-23-60/h2-5,8-11,13-22,24,29,32,42,44-50,63,71-72H,6-7,12,23,25-28,30-31,60-61H2,1H3,(H2,62,73)(H,64,77)(H,65,78)(H,66,79)(H,67,76)(H,68,74)(H,69,80)(H,70,75)/t32-,42-,44+,45+,46+,47-,48-,49+,50+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Displacement of [125I][LTT]SRIF28 from human cloned sst3 receptor by autoradiography				J Med Chem 51: 4030-7 (2008) Article DOI: 10.1021/jm701618q BindingDB Entry DOI: 10.7270/Q22J6CSW
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50243515 ((2R)-2-amino-N-[(4R,7S,10S,13R,16S,19S)-10-(4-amin...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C58H68ClN11O10S2/c1-32(71)50-58(80)69-49(56(78)65-45(51(62)73)27-35-13-18-36-8-2-3-9-37(36)24-35)31-82-81-30-48(68-52(74)42(61)25-33-14-19-39(59)20-15-33)57(79)66-46(26-34-16-21-40(72)22-17-34)54(76)67-47(28-38-29-63-43-11-5-4-10-41(38)43)55(77)64-44(53(75)70-50)12-6-7-23-60/h2-5,8-11,13-22,24,29,32,42,44-50,63,71-72H,6-7,12,23,25-28,30-31,60-61H2,1H3,(H2,62,73)(H,64,77)(H,65,78)(H,66,79)(H,67,76)(H,68,74)(H,69,80)(H,70,75)/t32-,42-,44+,45+,46+,47-,48-,49+,50+/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	296	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Displacement of [125I][LTT]SRIF28 from human cloned sst4 receptor by autoradiography				J Med Chem 51: 4030-7 (2008) Article DOI: 10.1021/jm701618q BindingDB Entry DOI: 10.7270/Q22J6CSW
					More data for this Ligand-Target Pair
Somatostatin receptor type 1 (Homo sapiens (Human))	BDBM50243515 ((2R)-2-amino-N-[(4R,7S,10S,13R,16S,19S)-10-(4-amin...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C58H68ClN11O10S2/c1-32(71)50-58(80)69-49(56(78)65-45(51(62)73)27-35-13-18-36-8-2-3-9-37(36)24-35)31-82-81-30-48(68-52(74)42(61)25-33-14-19-39(59)20-15-33)57(79)66-46(26-34-16-21-40(72)22-17-34)54(76)67-47(28-38-29-63-43-11-5-4-10-41(38)43)55(77)64-44(53(75)70-50)12-6-7-23-60/h2-5,8-11,13-22,24,29,32,42,44-50,63,71-72H,6-7,12,23,25-28,30-31,60-61H2,1H3,(H2,62,73)(H,64,77)(H,65,78)(H,66,79)(H,67,76)(H,68,74)(H,69,80)(H,70,75)/t32-,42-,44+,45+,46+,47-,48-,49+,50+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Displacement of [125I][LTT]SRIF28 from human cloned sst1 receptor by autoradiography				J Med Chem 51: 4030-7 (2008) Article DOI: 10.1021/jm701618q BindingDB Entry DOI: 10.7270/Q22J6CSW
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50243515 ((2R)-2-amino-N-[(4R,7S,10S,13R,16S,19S)-10-(4-amin...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C58H68ClN11O10S2/c1-32(71)50-58(80)69-49(56(78)65-45(51(62)73)27-35-13-18-36-8-2-3-9-37(36)24-35)31-82-81-30-48(68-52(74)42(61)25-33-14-19-39(59)20-15-33)57(79)66-46(26-34-16-21-40(72)22-17-34)54(76)67-47(28-38-29-63-43-11-5-4-10-41(38)43)55(77)64-44(53(75)70-50)12-6-7-23-60/h2-5,8-11,13-22,24,29,32,42,44-50,63,71-72H,6-7,12,23,25-28,30-31,60-61H2,1H3,(H2,62,73)(H,64,77)(H,65,78)(H,66,79)(H,67,76)(H,68,74)(H,69,80)(H,70,75)/t32-,42-,44+,45+,46+,47-,48-,49+,50+/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Displacement of [125I][LTT]SRIF28 from human cloned sst2 receptor by autoradiography				J Med Chem 51: 4030-7 (2008) Article DOI: 10.1021/jm701618q BindingDB Entry DOI: 10.7270/Q22J6CSW
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50243515 ((2R)-2-amino-N-[(4R,7S,10S,13R,16S,19S)-10-(4-amin...) Show SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(N)=O)NC(=O)[C@H](N)Cc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C58H68ClN11O10S2/c1-32(71)50-58(80)69-49(56(78)65-45(51(62)73)27-35-13-18-36-8-2-3-9-37(36)24-35)31-82-81-30-48(68-52(74)42(61)25-33-14-19-39(59)20-15-33)57(79)66-46(26-34-16-21-40(72)22-17-34)54(76)67-47(28-38-29-63-43-11-5-4-10-41(38)43)55(77)64-44(53(75)70-50)12-6-7-23-60/h2-5,8-11,13-22,24,29,32,42,44-50,63,71-72H,6-7,12,23,25-28,30-31,60-61H2,1H3,(H2,62,73)(H,64,77)(H,65,78)(H,66,79)(H,67,76)(H,68,74)(H,69,80)(H,70,75)/t32-,42-,44+,45+,46+,47-,48-,49+,50+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	n/a
University of Berne Curated by ChEMBL					Assay Description Displacement of [125I][LTT]SRIF28 from human cloned sst5 receptor by autoradiography				J Med Chem 51: 4030-7 (2008) Article DOI: 10.1021/jm701618q BindingDB Entry DOI: 10.7270/Q22J6CSW
					More data for this Ligand-Target Pair