BDBM50244208 CHEMBL4093017

SMILES: [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)CC1CCCCC1)C(O)=O

InChI Key: InChIKey=AQCRJOWGCAFEAA-CTIKTKRKSA-N

Data: 2 KI  2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50244208   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50244208 (CHEMBL4093017) Show SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)CC1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C16H24N2O5/c17-16(15(22)23)7-9(11-12(13(11)16)14(20)21)18-10(19)6-8-4-2-1-3-5-8/h8-9,11-13H,1-7,17H2,(H,18,19)(H,20,21)(H,22,23)/t9-,11-,12-,13-,16-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	425	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation counting				J Med Chem 61: 2303-2328 (2018) Article DOI: 10.1021/acs.jmedchem.7b01481 BindingDB Entry DOI: 10.7270/Q2W95CM9
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50244208 (CHEMBL4093017) Show SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)CC1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C16H24N2O5/c17-16(15(22)23)7-9(11-12(13(11)16)14(20)21)18-10(19)6-8-4-2-1-3-5-8/h8-9,11-13H,1-7,17H2,(H,18,19)(H,20,21)(H,22,23)/t9-,11-,12-,13-,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	627	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation counting				J Med Chem 61: 2303-2328 (2018) Article DOI: 10.1021/acs.jmedchem.7b01481 BindingDB Entry DOI: 10.7270/Q2W95CM9
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50244208 (CHEMBL4093017) Show SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)CC1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C16H24N2O5/c17-16(15(22)23)7-9(11-12(13(11)16)14(20)21)18-10(19)6-8-4-2-1-3-5-8/h8-9,11-13H,1-7,17H2,(H,18,19)(H,20,21)(H,22,23)/t9-,11-,12-,13-,16-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human mGlu3 receptor expressed in HEK cells assessed as reversal of DCG-4 inhibited forskolin-stimulated cAMP formation after ...				J Med Chem 61: 2303-2328 (2018) Article DOI: 10.1021/acs.jmedchem.7b01481 BindingDB Entry DOI: 10.7270/Q2W95CM9
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50244208 (CHEMBL4093017) Show SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)CC1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C16H24N2O5/c17-16(15(22)23)7-9(11-12(13(11)16)14(20)21)18-10(19)6-8-4-2-1-3-5-8/h8-9,11-13H,1-7,17H2,(H,18,19)(H,20,21)(H,22,23)/t9-,11-,12-,13-,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at human mGlu2 receptor expressed in HEK cells assessed as reversal of DCG-4 inhibited forskolin-stimulated cAMP formation after ...				J Med Chem 61: 2303-2328 (2018) Article DOI: 10.1021/acs.jmedchem.7b01481 BindingDB Entry DOI: 10.7270/Q2W95CM9
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50244208 (CHEMBL4093017) Show SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)CC1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C16H24N2O5/c17-16(15(22)23)7-9(11-12(13(11)16)14(20)21)18-10(19)6-8-4-2-1-3-5-8/h8-9,11-13H,1-7,17H2,(H,18,19)(H,20,21)(H,22,23)/t9-,11-,12-,13-,16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]pCCK-8 from cholecystokinin type B receptor in guinea pig brain membrane				J Med Chem 61: 2303-2328 (2018) Article DOI: 10.1021/acs.jmedchem.7b01481 BindingDB Entry DOI: 10.7270/Q2W95CM9
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50244208 (CHEMBL4093017) Show SMILES [H][C@]12[C@H](C(O)=O)[C@@]1([H])[C@@](N)(C[C@@H]2NC(=O)CC1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C16H24N2O5/c17-16(15(22)23)7-9(11-12(13(11)16)14(20)21)18-10(19)6-8-4-2-1-3-5-8/h8-9,11-13H,1-7,17H2,(H,18,19)(H,20,21)(H,22,23)/t9-,11-,12-,13-,16-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human mGlu3 receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP formation after 20 mins by HTRF a...				J Med Chem 61: 2303-2328 (2018) Article DOI: 10.1021/acs.jmedchem.7b01481 BindingDB Entry DOI: 10.7270/Q2W95CM9
					More data for this Ligand-Target Pair