BDBM50244229 3-acetyl-7-chloro-4-methylimidazo[1,5-a]quinazolin-5(4H)-one::CHEMBL458320

SMILES: CC(=O)c1ncn2c1n(C)c(=O)c1cc(Cl)ccc21

InChI Key: InChIKey=ZZRJCUKLHRXQOS-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244229   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM50244229 (3-acetyl-7-chloro-4-methylimidazo[1,5-a]quinazolin...) Show SMILES CC(=O)c1ncn2c1n(C)c(=O)c1cc(Cl)ccc21 Show InChI InChI=1S/C13H10ClN3O2/c1-7(18)11-12-16(2)13(19)9-5-8(14)3-4-10(9)17(12)6-15-11/h3-6H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Moltech Corporation Curated by ChEMBL					Assay Description Binding affinity to GABAA alpha-5-beta-2-gamma-2 receptor				J Med Chem 51: 3788-803 (2008) Article DOI: 10.1021/jm701433b BindingDB Entry DOI: 10.7270/Q2FQ9XH6
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50244229 (3-acetyl-7-chloro-4-methylimidazo[1,5-a]quinazolin...) Show SMILES CC(=O)c1ncn2c1n(C)c(=O)c1cc(Cl)ccc21 Show InChI InChI=1S/C13H10ClN3O2/c1-7(18)11-12-16(2)13(19)9-5-8(14)3-4-10(9)17(12)6-15-11/h3-6H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Moltech Corporation Curated by ChEMBL					Assay Description Binding affinity to GABAA alpha-1-beta-3-gamma-2 receptor				J Med Chem 51: 3788-803 (2008) Article DOI: 10.1021/jm701433b BindingDB Entry DOI: 10.7270/Q2FQ9XH6
					More data for this Ligand-Target Pair