BDBM50244538 1-[6-(4-Methanesulfonyl-phenoxy)-5-nitro-pyrimidin-4-yl]-piperidine-4-carboxylic acid ethyl ester::CHEMBL452825

SMILES: CCOC(=O)C1CCN(CC1)c1ncnc(Oc2ccc(cc2)S(C)(=O)=O)c1[N+]([O-])=O

InChI Key: InChIKey=GXDYPCVLMNSCLA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50244538 (1-[6-(4-Methanesulfonyl-phenoxy)-5-nitro-pyrimidin...) Show SMILES CCOC(=O)C1CCN(CC1)c1ncnc(Oc2ccc(cc2)S(C)(=O)=O)c1[N+]([O-])=O Show InChI InChI=1S/C19H22N4O7S/c1-3-29-19(24)13-8-10-22(11-9-13)17-16(23(25)26)18(21-12-20-17)30-14-4-6-15(7-5-14)31(2,27)28/h4-7,12-13H,3,8-11H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR119 (unknown origin) expressed in HEK293 cells assessed as cAMP level by flash plate assay				J Med Chem 51: 5172-5 (2008) Article DOI: 10.1021/jm8006867 BindingDB Entry DOI: 10.7270/Q2KW5FVB
					More data for this Ligand-Target Pair